Vinpocetine Capsules – 15mg
Vinpocetine Capsules (15mg) contain a highly purified, standardized quantity of ethyl apovincaminate (systematically designated as ethyl (3$\alpha$,16$\alpha$)-apovincamenine-14-carboxylate). Derived through semi-synthetic modification of vincamine—a natural alkaloid isolated from the leaves of the Vinca minor (lesser periwinkle) plant—vinpocetine is widely utilized across neuropharmacological research, cognitive aging trials, and cellular metabolomic studies. Encapsulated into uniform 15mg solid doses under strict quality control parameters, these capsules provide a highly stable and practical delivery format for laboratory evaluation, in vitro assay calibrations, and comparative vascular modeling.
Sourcing this vinca alkaloid derivative in a pre-measured capsule format offers notable handling and stability advantages. The protective outer shell preserves the chemical integrity of the active crystalline powder inside, shielding it from light-induced oxidation and ambient moisture, while completely eliminating the scale errors and particulate airborne dispersion hazards encountered when weighing loose bulk material.
The Advantages of Standardized 15mg Capsule Formats
Utilizing Vinpocetine Capsules (15mg) rather than loose bulk powder introduces essential operational controls that safeguard experimental precision and protect the structural integrity of your chemical repository.
1. Mitigation of Aerosolization and Atmospheric Contamination
Raw alkaloid powders are highly prone to static accumulation, which can cause fine particles to cling to weighing vessels or drift through laboratory drafts. Unintentional airborne particulate migration represents a major vector for cross-contamination and manual handling loss. The encapsulated solid design completely secures the crystalline matrix, allowing laboratory staff to handle, transfer, and isolate the exact active mass with complete volumetric safety.
2. High Unit Homogeneity and Long-Term Archival Longevity
Vinpocetine freebase and salt structures are sensitive to environmental oxidation and thermal variations over extended storage cycles. The capsule barrier minimizes the active surface area exposed to ambient environmental factors, significantly reducing moisture absorption or chemical breakdown. Combined with uniform industrial blending, each individual capsule delivers an exact, unvarying 15mg payload ($\pm 0.5\%$), protecting multi-week longitudinal baseline tracking from concentration drift.
The Structural Science of Vinpocetine
The molecular framework of Vinpocetine serves as a vital point of comparison within modern cerebrovascular and neuroprotective research. Detailed data profiles curated in the National Center for Biotechnology Information (NCBI) PubChem Database highlight that the deliberate modification of the base vincamine structure into an ethyl ester configuration profoundly enhances its relative lipid solubility and alters its kinetic behaviors during in vitro cell-line modeling.
1. Specific Phosphodiesterase and Ion Channel Inhibition
The primary biochemical activities of Vinpocetine are strictly dictated by its unique pentacyclic alkaloid architecture:
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PDE1 Isoenzyme Selectivity: In vitro binding models demonstrate that vinpocetine acts as a selective inhibitor of voltage-dependent, calcium/calmodulin-dependent phosphodiesterase type 1 ($PDE1$). This selective block increases intracellular concentrations of cyclic adenosine monophosphate ($cAMP$) and cyclic guanosine monophosphate ($cGMP$), facilitating smooth muscle relaxation in vascular beds.
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Sodium and Calcium Channel Modulation: In vitro functional assays show that the compound blocks voltage-gated sodium ($Na^+$) channels and L-type calcium ($Ca^{2+}$) channels in a frequency-dependent manner, helping to mitigate cellular excitotoxicity and stabilize neuronal membranes under conditions of metabolic stress.
2. Solution Kinetics and Reconstitution Matrix
The crystalline powder enclosed within the capsules is engineered for rapid dissociation when introduced to appropriate analytical carrier fluids:
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Lipophilic Solubility Profile: While vinpocetine exhibits low solubility in purely neutral aqueous media, it dissolves smoothly in slightly acidic environments, or standard laboratory solvents like methanol, ethanol, and dimethyl sulfoxide ($DMSO$).
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Streamlined Molar Formulations: Because each solid capsule provides a validated 15mg chemical standard, research facilities can bypass initial micro-gram powder weighing steps, minimizing processing times and eliminating weighing-scale discrepancies.
Technical Specifications: Vinpocetine 15mg Capsule Assay
To preserve objective analytical standards for seamless laboratory integration, all promotional descriptions are omitted in favor of verified empirical chemical values.
| Parameter | Detailed Empirical Specification |
| Chemical Identification | Ethyl apovincaminate (Vinpocetine) |
| Common Trade References | Cavinton / Intelectol |
| Substance Classification | Vinca Alkaloid Derivatives / Cerebrovascular Agonists |
| CAS Registry Number | 42971-09-5 |
| Systemic Purity Level | ≥99.0% Active Compound Purity verified via HPLC |
| Molecular Formula | $C_{22}H_{26}N_{2}O_{2}$ |
| Exact Formula Weight | 350.45 g/mol |
| Active Capsule Mass | 15mg Active Ingredient per encapsulated unit |
Frequently Asked Questions Regarding Laboratory Compliance
What are the primary solubility thresholds of this compound?
Vinpocetine is highly lipophilic and practically insoluble in water at neutral pH. It dissolves efficiently in dilute aqueous acids (pH less than 3.0), as well as in high-purity laboratory methanol, anhydrous ethanol, and acetone, making it highly adaptable for automated liquid chromatography-mass spectrometry (LC-MS) target lines.
How should this material be stored to prevent spontaneous degradation?
To maximize stability and prevent moisture absorption, store the capsules in their original tightly sealed container within a cool, dry environment completely shielded from direct UV exposure. Controlled room temperatures between 15°C and 25°C are adequate for standard projects; however, for long-term archival archives, keeping the sealed containers under dark, desiccated conditions will completely halt any trace molecular breakdown. For comprehensive safety protocols and international handling guidelines, researchers can consult documentation provided by the European Chemicals Agency (ECHA).
Is this chemical compound approved for diagnostic human injection or dietary distribution?
Regulatory status varies significantly by global jurisdiction. In many regions, vinpocetine is utilized clinically for treating cerebrovascular disorders or available as a dietary supplement. However, this specific material is refined and packaged strictly for in vitro laboratory analysis, forensic identification, and scientific research. It is explicitly not approved for human consumption, veterinary trials, or direct clinical intervention within this laboratory reference framework.
Secure Industrial Chemical Excellence
Do not compromise your laboratory’s analytical data or ongoing research cycles on unverified, loosely handled chemical products that exhibit heavy localized degradation. By selecting our Vinpocetine Capsules (15mg), you introduce uncompromising laboratory purity, verifiable chemical stability, and immaculate baseline precision into your experimental workflow. The resulting mitigation of trace impurities, highly predictable solubility profiles, and clear assay metrics will empower your research collective to break through analytical plateaus with absolute, unwavering confidence.
